Worried about premature skin aging?
Coco Chanel once said, “Nature gives you the face you have at twenty; it is up to you to merit the face you have at fifty.”
Let’s face it. For thousands of years, men and women have pursued the fountain of youth. Anti-aging therapies have come a long way! In this article, we will explore our top 3 impressive anti-aging therapies that every woman needs to know about along with each other their own:
- Efficacy & Safety
- Side Effects
- and more!
The Anti-Aging Evolution
You’re not the only one who’s interested in maintaining your youthful glow. Let’s track down famous people with their anti-aging rituals and quests.
Cleopatra, Egyptian queen: She bathed in sour donkey’s milk squeezed from 7,000 donkeys. She probably got it right since milk contains alpha-hydroxy or lactic acid. This peels-off skin, leaving it smooth and blemish-free. She also used crocodile dung to enhance her complexion. Ew!
Galen, the Greek physician: He invented the cold cream. It forms an emulsion of beeswax, water, olive oil, and scents. It smooths the skin and removes impurities.
Juan Ponce de León, Spanish conquistador: He journeyed far and wide in search of the eternal fountain of youth, literally. His efforts weren’t entirely futile since he stumbled upon Florida…although not exactly anti-aging.
Elizabeth I, Queen of England: Her royal highness used Venetian ceruse as a skin-whitener. It’s composed of white lead and vinegar. Unfortunately, lead causes greying skin and wrinkles. To help hide these adverse effects, Elizabethan women glazed their faces with raw eggs.
Margaret Kroesen: Sometime in 1889, her daughter’s frown lines inspired her to develop a wrinkle smoothing-patch. Frownies, as it was called, helped smooth the skin.
The Anti-Aging Revolution
By the 20th century, the beauty and cosmetics industry started manufacturing a wide array of anti-aging products. These are cosmetic hormone creams, albumin wrinkle smoother, retinol or Retin-A, Botox, vitamin C serum, hydraulic acid, moisturizers, and sunscreens.
You apply these products on your skin. Although these products do help, skin aging goes deeper than the outer layer of skin. Some skin wrinkles, scars, or stretch marks need more than the regular application of anti-aging products for long-term effects.
Microneedling and its Benefits
Microneedling, also called dermarolling, was first described in 1995 as percutaneous collagen induction. A trained healthcare provider uses a microneedle device in this minimally invasive procedure. Fine needles run over your skin creating pinpricks. The pinholes stimulate wound healing and the production of collagen and elastin. This minimizes acne scars, fine lines, and photo-aging. It’s perfect for scar revision, skin revitalization, texture improvement, stretch marks, body scars, and thinning hair. The pinholes on the skin also become a way for introducing skin-care products…like the peptide GHK-Cu.
Microneedling is Effective and Safe
Yes, microneedling is an effective and safe therapeutic option for various skin conditions . This was concluded by researchers who conducted a comprehensive review of microneedling. They looked into PubMed, Medline, and ScienceDirect studies to support this claim. These studies included people as study subjects who have undergone random trials. Based on their review, microneedling resolved skin problems such as acne, excessive sweating (hyperhidrosis), hair loss (alopecia), scars, gray or brown patches (melasma), and overexposure to UV light (photodamage).
Book a FREE Microneedling Consult!
Perfect for Fine Lines, Acne Scars, Photo-Aging, Scar Revision, Skin Revitalization, Texture Improvement, Stretch Marks / Body Scars, and Thinning Hair! For inquiries, call 505-445-4300 or book a FREE consult here!
Microneedling: Side Effects
You may experience minor discomfort as the microneedle works on your skin. Before the therapy though, a mild topical anesthetic is applied over your skin. Since your skin has pinholes, you may unintentionally apply products that contain toxic substances. These substances get into the pinholes of your skin. It then causes harmful reactions once absorbed by your body. So, you have to make sure the products you’re using are approved by your healthcare provider. Patients experience mild redness for about 24hours, which is much more manageable than the downtime experience with laser frequency and laser ablation.
Microneedling: The Procedure
Results are noted after one session, but maximum improvement occurs with four sessions, which are spaced four to six weeks apart. This downtime allows for skin repair and growth. According to the study result of Ablon, microneedling therapy showed an improvement in lines, wrinkles, skin laxity, and texture after 90-150 days from the first session.
Microneedling: Effective means for peptide delivery
Peptides such as GHK-Cu stimulate collagen production and are beneficial for the appearance and health of the skin. Microneedling enhances skin penetration and offers an effective means to deliver peptides under the surface of the skin.
GHK-Cu (copper peptide)
Discovered in 1973, GHK-Cu or glycyl-L-histidyl-L-lysine is a naturally occurring copper tripeptide. It can be found in your plasma, saliva, and urine. It aids in metabolism, promotes wound healing, and prevents liver damage.GHK-Cu benefits your skin in many ways. Its antiaging property reduces your fine lines and deep wrinkles. It also smoothens, tightens, and clears your skin. Its other positive effects include reducing skin spots or blemishes as it protects you from harmful UV radiation. GHK-Cu is not only good for your skin but your hair, too. It promotes the growth and thickness of your hair.
GHK-Cu is effective and safe
- Yes, GHK-Cu is safe as it repairs, regenerates, and protects the skin (Pickart and Margolina, 2018). This is based on a study they conducted to determine the regenerative and protective action of GHK-Cu on the skin.
- Its effects are anti-inflammatory and antioxidant. It serves as a response signal or protects your tissue after you suffer a skin injury. Its anti-inflammatory effect controls oxidative stress which can further damage your tissues that contributes to aging.
- GHK-Cu is most abundant during childhood and declines with age. As you grow older, there is thus increased risk for tissue destruction, inflammation, and even cancer.
GHK-Cu has also been widely used in cosmetics with its anti-aging and reparative effects. Studies have been conducted to confirm its efficacy:
- GHK-Cu topical cream did better than retinoic acid and vitamin C in boosting the collagen of 20 women who had photodamaged skin.
- GHK-Cu facial cream improved the skin appearance, clarity, and tautness of 71 women who participated in a 12-week study. Compared with placebo cream, the researchers noted that GHK-Cu increased skin thickness and density. It also lessened the depth of wrinkles and fine lines.
- GHK-Cu eye cream did better than vitamin K in reducing wrinkles and lines, increased thickness and density of the skin, and improved its appearance.
- GHK-Cu cream stimulated the reproduction of the cells of the outer layer of the skin. Based on the same study, it also improved the skin’s density, appearance, and thickness.
No adverse effects
- GHK-Cu was found to be non-irritating and non-toxic in at least three separate experiments. It has no adverse effects and can be incorporated in creams, dermal patches, foams, liposomes, microneedles, or subcutaneous injections.
- GHK-Cu’s formulation as a topical solution works for wound healing and anti-aging.
Two other cosmeceutical peptides
- Argireline® peptide: Argireline (Arg) is a brand name of acetyl hexapeptide-3 or acetyl hexapeptide-8. Arg, a neurotransmitter, reduces the movement of your muscles to prevent the formation of wrinkles.It reduces your expression or fine lines, stimulates the production of collagen, and promotes moisture of your skin. It’s like botulinum toxin (Botox) with its wrinkle-smoothing effect. A study mentioned that Arg is safer than Botox with an efficacy rate of 48% with twice a day usage for four weeks. The researchers’ study revealed Arg3 was most effective among other Arg peptides they tested (Lim et al., 2018). There’re still no known side effects of Arg. Thus, it is safe for you.
- Leuphasyl® peptide: Leuphasyl is a brand name of pentapeptide-3. It modulates the release of acetylcholine, a neurotransmitter, which reduces the contraction of muscles. This peptide goes hand-in-hand with Arg and other peptides. Its benefits are like Arg, with focus on your forehead and around your eyes. It’s less effective than Botox, but it has no side effects (Dragomirescu et al., 2014). Thus, it is also safe for you.
Glutathione & Its Benefits
GSH, dubbed the “master antioxidant”, is a tripeptide of cysteine, glycine, and glutamic acid. It’s a naturally occurring substance produced in the liver. It’s also found in meats, vegetables, and fruits. It has been known to allegedly treat some diseases. To name a few, these are cataracts, cancer, diabetes, Alzheimer’s, and osteoarthritis. In general, GSH promotes longevity, protects the body from toxins, and maintains health (Pizzorno, 2014).
Glutathione Is effective for anti-aging
GSH is widely used for skin-lightening as it lessens age spots and dark marks. And, it lessens the pigmentation (melanin) in your skin.Research suggests you take it with vitamin C of equal or twice the dosage for best results (Priyadarshini, 2015). We find that glutathione improves the skin’s glow. As an antioxidant, GSH cleanses the liver and kidneys of toxins for a healthier and refreshed-looking skin.
GSH has also been shown to improve skin elasticity and helps reduce wrinkles or fine lines (Weschawalit et al., 2017). Collagen synthesis is likewise enhanced by GSH (Shan et al., 1994). It works by regulating the transforming growth factor (TGF), which stimulates the production of collagen (Liu et al., 2004).
GSH can be taken in three routes; by mouth, nasal spray, or IV. For optimal results, GSH IV infusion is recommended.
Glutathione: Side Effects
GSH intravenous (IV) has no known significant side effects. GSH IV was observed to have no potential adverse reactions and its short half-life indicated limited duration of its effectiveness. (Fukagawa et al., 1996).It was observed to be safe and tolerated by people with Parkinson’s disease in a study conducted at the University of South Florida (Hauser et al., 2009). The study by Hauser was validated by a related study as a person did not notice any adverse effects during GSH IV infusion (Otto et al., 2018)A review of related literature pointed out that GSH had no or minimal adverse effects, but further studies were suggested to assess its safety (Davids et al., 2017).
Ready to get the drip?
Microneedling, GHK-Cu, and Glutathione are only some of anti-aging therapies available in our clinic. For inquiries, call 505-445-4300 or email us at email@example.com today!